{"id":14453,"date":"2019-06-28T19:03:32","date_gmt":"2019-06-28T17:03:32","guid":{"rendered":"https:\/\/www.hollandbio.nl\/?p=14453"},"modified":"2019-07-02T19:05:50","modified_gmt":"2019-07-02T17:05:50","slug":"the-winner-of-the-venture-challenge-spring-2019-is-ambagon","status":"publish","type":"post","link":"https:\/\/www.hollandbio.nl\/en\/nieuws\/the-winner-of-the-venture-challenge-spring-2019-is-ambagon\/","title":{"rendered":"The winner of the Venture Challenge Spring 2019 is AmbAgon"},"content":{"rendered":"\n<h2 class=\"wp-block-heading\">First-in-class drugs through targeted stabilisation of protein complexes<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>During the Dutch Biotech Event where biotech companies of all sizes, from start-ups to scale-ups,\u00a0meet and get\u00a0inspired,\u00a0the\u00a0LifeSciences@Work\u00a0Venture Challenge was annouced. This year\u2019s winner of the Spring edition became\u00a0AmbAgon.\u00a0The\u00a0Eindhoven-based\u00a0start-up\u00a0develops small-molecule therapeutics for breast cancer\u00a0by augmenting the tumor-suppressing functions of the 14-3-3 protein.<\/strong><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">According to the&nbsp;jury,&nbsp;led by Carine van den Brink,&nbsp;AmbAgon&nbsp;has a strong team that, with their unique combination of expertise, has discovered a new&nbsp;approach towards developing drugs for metastatic&nbsp;breast cancer.&nbsp;A ground breaking&nbsp;method that change the future of cancer patients and their&nbsp;therapy&nbsp;accurance.&nbsp;&nbsp;<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">AmbAgon&nbsp;has developed small molecule screening technologies&nbsp;focused on discovering molecules that stabilize the direct interaction of oncogenic transcription factors with so-called 14-3-3 proteins, thereby inhibiting their pathological activities. This approach, to augment the endogenous tumor-suppressing functions of 14-3-3 within different breast cancer types with small molecule drugs, provides for a radically new entry.&nbsp;A method that&nbsp;has been long sought for by the pharmaceutical industry and which is urgently needed in the clinic.&nbsp;<\/p>\n\n\n\n<blockquote class=\"wp-block-quote is-layout-flow wp-block-quote-is-layout-flow\"><p>Luc Brunsveld, AmbAgon: &#8220;The Venture Challenge has been a fantastic learning&nbsp;experience&nbsp;for us. It brought us into contact with the Dutch biotech community. Winning this&nbsp;challenge is the absolute icing on the cake.&#8221;<\/p><\/blockquote>\n\n\n\n<p class=\"wp-block-paragraph\">The Venture Challenge&nbsp;Spring 2019&nbsp;started in&nbsp;April&nbsp;this year and ended today&nbsp;at&nbsp;the Dutch&nbsp;Biotech Event, where&nbsp;<a href=\"https:\/\/www.lifesciencesatwork.nl\/profile\/ambagon\/\" target=\"_blank\" rel=\"noreferrer noopener\">AmbAgon<\/a>&nbsp;takes&nbsp;home the \u20ac25.000 prize money&nbsp;to invest in their&nbsp;growth.&nbsp;The other&nbsp;highly-motivated&nbsp;participating teams were:\u202f&nbsp;<a href=\"https:\/\/www.lifesciencesatwork.nl\/profile\/mission_ms\/\" target=\"_blank\" rel=\"noreferrer noopener\">MissionMS<\/a>,&nbsp;<a href=\"https:\/\/www.lifesciencesatwork.nl\/profile\/multiscreening\/\" target=\"_blank\" rel=\"noreferrer noopener\">MULTISCREENING<\/a>,&nbsp;<a href=\"https:\/\/www.lifesciencesatwork.nl\/profile\/praxa-sense\/\" target=\"_blank\" rel=\"noreferrer noopener\">Praxa&nbsp;Sense<\/a>, and&nbsp;<a href=\"https:\/\/www.lifesciencesatwork.nl\/profile\/ufo-biosciences\/\" target=\"_blank\" rel=\"noreferrer noopener\">UFO Biosciences<\/a>. Participating in the Venture Challenge leads to a clear venture plan, as well as to investor-ready pitches. The\u202f&nbsp;<a href=\"https:\/\/www.lifesciencesatwork.nl\/\" target=\"_blank\" rel=\"noreferrer noopener\">LifeSciences@Work&nbsp;Accelerator<\/a>&nbsp;\u202fis powered by \u202f<a href=\"https:\/\/www.health-holland.com\/\" target=\"_blank\" rel=\"noreferrer noopener\">Health~Holland<\/a>, Top Sector Life Sciences &amp; Health.&nbsp;<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Contact&nbsp;<a href=\"mailto:l.brunsveld@tue.nl\" target=\"_blank\" rel=\"noreferrer noopener\">Luc&nbsp;Brunsveld<\/a>&nbsp;for more information about&nbsp;AmbAgon.<\/p>\n\n\n\n<h3 class=\"wp-block-heading\">Venture Challenge Fall 2019:<br>Call open!&nbsp;&#8211; Deadline: 5 September 2019<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">Our specialised coaching focuses on developing your initial idea into a solid business during a series of\u00a0boot camps and\u00a01-on-1 coaching and mentoring sessions.\u00a0Startup teams learn\u00a0to\u00a0identify key risks, analyse customer value propositions, develop a validation strategy, learn to build a venture plan\u00a0and, ultimately,\u00a0get connected\u00a0to Life Sciences experts, investors and seasoned entrepreneurs.\u00a0<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Source: <a href=\"https:\/\/www.health-holland.com\/news\/2019\/06\/the-winner-of-the-venture-challenge-is-ambagon\"><strong>Health~Holland<\/strong><\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>First-in-class drugs through targeted stabilisation of protein complexes During the Dutch Biotech Event where biotech companies of all sizes, from start-ups to scale-ups,\u00a0meet and get\u00a0inspired,\u00a0the\u00a0LifeSciences@Work\u00a0Venture Challenge was annouced. This year\u2019s winner of the Spring edition became\u00a0AmbAgon.\u00a0The\u00a0Eindhoven-based\u00a0start-up\u00a0develops small-molecule therapeutics for breast cancer\u00a0by augmenting the tumor-suppressing functions of the 14-3-3 protein. According to the&nbsp;jury,&nbsp;led by Carine van [&hellip;]<\/p>\n","protected":false},"author":6,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[57,43],"tags":[],"class_list":["post-14453","post","type-post","status-publish","format-standard","hentry","category-ijzersterk-innovatieklimaat","category-innovatieklimaat"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v28.0 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>The winner of the Venture Challenge Spring 2019 is AmbAgon - hollandbio<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.hollandbio.nl\/en\/nieuws\/the-winner-of-the-venture-challenge-spring-2019-is-ambagon\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"The winner of the Venture Challenge Spring 2019 is AmbAgon - hollandbio\" \/>\n<meta property=\"og:description\" content=\"First-in-class drugs through targeted stabilisation of protein complexes During the Dutch Biotech Event where biotech companies of all sizes, from start-ups to scale-ups,\u00a0meet and get\u00a0inspired,\u00a0the\u00a0LifeSciences@Work\u00a0Venture Challenge was annouced. This year\u2019s winner of the Spring edition became\u00a0AmbAgon.\u00a0The\u00a0Eindhoven-based\u00a0start-up\u00a0develops small-molecule therapeutics for breast cancer\u00a0by augmenting the tumor-suppressing functions of the 14-3-3 protein. 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